Wednesday, October 17, 2012


  • heart valve is critical to blood flow
  • the efficiency is dictated by the shape, tissue, and biomechanics
  • mechanical valves are good but high risk of clots
  • tissue engineering looks a a viable replacement to invasive procedures and mechanical heart valves
  • start with a type of biodegradable structural material made of fibrin and collagen 
  • cells are than put on it to grow a valve
  • inkjet, laser, and assisted bioprinting have made it possible to come up with more complex biomaterials
  • 3D bioprinting has proven a good way to create 3D structures for things like blood vessels and liver
  • hydrogel is in the relatively early stages of design
  • it is has been studied in mainly simple structures 
  • in hydrogelling a  gridded pattern of tissue is laid down for a support structure for the cells to sit upon
  • the proper accuracy must be made of the grid pattern measuring overlap and gaps
  • cells are placed on it to grow into the structure that it is laid out to be
  • there is a multiple syringe method used to make complex structures
  • the proper material is layered on to create the proper form for the tissue

1 comment:

  1. This is a very interesting article it seems like. Very, very cool technology that seems to leave anything i have ever seen in the dust. Especially how it seems capable of doing "complex structures" which can possibly save millions. Also, it seems to be a possible outlet to an entirely new type of science. Which from how it sounds will change the medical world entirely for clot protection.

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